منابع مشابه
Therapeutic trials in acute gouty arthritis.
Colchicine remains the agent of choice in the treatment of acute gouty arthritis. In recent years valuable additions to the therapeutic armamentarium in this disease include ACTH, cortisone, hydrocortisone acetate, prednisone, and Butazolidin (Wolfson, Hunt, Cohn, Robinson, and Duff, 1950; Gutman and Yu, 1950, 1952; Freyberg, 1955; Hartung, 1955; Steinbrocker, Neustadt, and Ehrlich, 1954). All ...
متن کاملColchicine in acute gouty arthritis: the optimum dose?
We applaud Cronstein and Terkeltaub [1] on their comprehensive review of the inflammatory process of gout and its treatment. Although they allude to the fact that colchicine probably has the smallest therapeutic window of any drug used to treat acute gouty arthritis, they have suggested " In treating acute gouty arthritis colchicine is typically administered as an oral 0.6 mg dose, followed by ...
متن کاملRegimen of indomethacin therapy in acute gouty arthritis.
Though colchicine has been famed for centuries for its effect in acute gouty arthritis its relief of pain and inflammation in this condition is not invariable and may not be apparent for 24 hours or more. It was therefore not surprising that when phenylbutazone was introduced colchicine was largely replaced by this preparation, which was more certain in its action. Highdosage phenylbutazone the...
متن کاملIncreased circulating Th22 cells in patients with acute gouty arthritis
BACKGROUND T-helper 22 (Th22) cells are involved in host immunity against pathogen invasion and have been implicated in the pathogenesis of inflammatory diseases. However, the roles of Th22 cells in acute gouty arthritis remain unclear. METHODS A case-control study was employed to illustrate the clinical significance of Th22 cells in acute gouty arthritis. In this study, 27 patients with acut...
متن کاملThe tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice
Gouty arthritis is caused by the deposition of monosodium urate (MSU) crystals in joints. Despite many treatment options for gout, there is a substantial need for alternative treatments for patients unresponsive to current therapies. Tyrosine kinase inhibitors have demonstrated therapeutic benefit in experimental models of antibody-dependent arthritis and in rheumatoid arthritis in humans, but ...
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ژورنال
عنوان ژورنال: Journal of Nepal Medical Association
سال: 2003
ISSN: 1815-672X,0028-2715
DOI: 10.31729/jnma.788